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BMCBI
2007
128views more  BMCBI 2007»
13 years 7 months ago
Detailed estimation of bioinformatics prediction reliability through the Fragmented Prediction Performance Plots
Background: An important and yet rather neglected question related to bioinformatics predictions is the estimation of the amount of data that is needed to allow reliable predictio...
Oliviero Carugo
BMCBI
2008
137views more  BMCBI 2008»
13 years 7 months ago
A dynamic Bayesian network approach to protein secondary structure prediction
Background: Protein secondary structure prediction method based on probabilistic models such as hidden Markov model (HMM) appeals to many because it provides meaningful informatio...
Xin-Qiu Yao, Huaiqiu Zhu, Zhen-Su She
BMCBI
2008
116views more  BMCBI 2008»
13 years 7 months ago
Impact of residue accessible surface area on the prediction of protein secondary structures
Background: The problem of accurate prediction of protein secondary structure continues to be one of the challenging problems in Bioinformatics. It has been previously suggested t...
Amir Momen-Roknabadi, Mehdi Sadeghi, Hamid Pezeshk...
BMCBI
2004
177views more  BMCBI 2004»
13 years 7 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
BMCBI
2007
59views more  BMCBI 2007»
13 years 7 months ago
Environment specific substitution tables for thermophilic proteins
Background: Thermophilic organisms are able to live at high temperatures ranging from 50 to > 100°C. Their proteins must be sufficiently stable to function under these extreme...
K. Mizuguchi, M. Sele, Maria Vittoria Cubellis