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BMCBI
2011
12 years 11 months ago
Determinants of Antigenicity and Specificity in immune response for Protein Sequences
Background: Target specific antibodies are pivotal for the design of vaccines, immunodiagnostic tests, studies on proteomics for cancer biomarker discovery, identification of prot...
Yulong Wang, Wenjun Wu, Nicolas N. Negre, Kevin P....
BMCBI
2010
107views more  BMCBI 2010»
13 years 2 months ago
Interaction prediction and classification of PDZ domains
Background: PDZ domain is a well-conserved, structural protein domain found in hundreds of signaling proteins that are otherwise unrelated. PDZ domains can bind to the C-terminal ...
Sibel Kalyoncu, Ozlem Keskin, Attila Gürsoy
BMCBI
2007
130views more  BMCBI 2007»
13 years 7 months ago
Exploiting residue-level and profile-level interface propensities for usage in binding sites prediction of proteins
Background: Recognition of binding sites in proteins is a direct computational approach to the characterization of proteins in terms of biological and biochemical function. Residu...
Qiwen Dong, Xiaolong Wang, Lei Lin, Yi Guan
BMCBI
2007
142views more  BMCBI 2007»
13 years 7 months ago
Predicting and improving the protein sequence alignment quality by support vector regression
Background: For successful protein structure prediction by comparative modeling, in addition to identifying a good template protein with known structure, obtaining an accurate seq...
Minho Lee, Chan-seok Jeong, Dongsup Kim
AIIA
2005
Springer
14 years 1 months ago
BIOPACMAS: A Personalized, Adaptive, and Cooperative MultiAgent System for Predicting Protein Secondary Structure
In this paper, we illustrate an application aimed at predicting protein secondary structure. The proposed system has been devised using PACMAS, a generic architecture designed to s...
Giuliano Armano, Gianmaria Mancosu, Alessandro Orr...