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BMCBI
2006
161views more  BMCBI 2006»
13 years 7 months ago
A novel approach to phylogenetic tree construction using stochastic optimization and clustering
Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
Ling Qin, Yixin Chen, Yi Pan, Ling Chen
CSB
2005
IEEE
223views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Automatic Protein Function Annotation through Candidate Ortholog Clusters from Incomplete Genomes
Annotation of protein function often arises in the context of partially complete genomes but is not adequately addressed. We present an annotation method by extracting ortholog cl...
Akshay Vashist, Casimir A. Kulikowski, Ilya B. Muc...
ATAL
2006
Springer
13 years 11 months ago
Efficient agent-based models for non-genomic evolution
Modeling dynamical systems composed of aggregations of primitive proteins is critical to the field of astrobiological science, which studies early evolutionary structures dealing ...
Nachi Gupta, Adrian K. Agogino, Kagan Tumer
BMCBI
2008
124views more  BMCBI 2008»
13 years 7 months ago
Inferring modules of functionally interacting proteins using the Bond Energy Algorithm
Background: Non-homology based methods such as phylogenetic profiles are effective for predicting functional relationships between proteins with no considerable sequence or struct...
Ryosuke Watanabe, Enrique Morett, Edgar E. Vallejo
TCBB
2011
13 years 2 months ago
Graph Comparison by Log-Odds Score Matrices with Application to Protein Topology Analysis
A TOPS diagram is a simplified description of the topology of a protein using a graph where nodes are α-helices and β-strands, and edges correspond to chirality relations and p...
J. Rocha