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PKDD
2007
Springer
87views Data Mining» more  PKDD 2007»
14 years 1 months ago
Visual Exploration of Genomic Data
Abstract. In this study, we present methods for comparative visualization of DNA sequences in two dimensions. First, we illustrate a transformation of gene sequences into numerical...
Michail Vlachos, Bahar Taneri, Eamonn J. Keogh, Ph...
EVOW
2009
Springer
14 years 2 months ago
Validation of a Morphogenesis Model of Drosophila Early Development by a Multi-objective Evolutionary Optimization Algorithm
We apply evolutionary computation to calibrate the parameters of a morphogenesis model of Drosophila early development. The model aims to describe the establishment of the steady g...
Rui Dilão, Daniele Muraro, Miguel Nicolau, ...
BMCBI
2007
216views more  BMCBI 2007»
13 years 7 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos
BMCBI
2008
146views more  BMCBI 2008»
13 years 7 months ago
Can molecular dynamics simulations help in discriminating correct from erroneous protein 3D models?
Background: Recent approaches for predicting the three-dimensional (3D) structure of proteins such as de novo or fold recognition methods mostly rely on simplified energy potentia...
Jean-François Taly, Antoine Marin, Jean-Fra...
BMCBI
2004
133views more  BMCBI 2004»
13 years 7 months ago
Evaluation of several lightweight stochastic context-free grammars for RNA secondary structure prediction
Background: RNA secondary structure prediction methods based on probabilistic modeling can be developed using stochastic context-free grammars (SCFGs). Such methods can readily co...
Robin D. Dowell, Sean R. Eddy