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BMCBI
2008
107views more  BMCBI 2008»
13 years 7 months ago
GPR17: Molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2
Background: GPR17 is a G-protein-coupled receptor located at intermediate phylogenetic position between two distinct receptor families: the P2Y and CysLT receptors for extracellul...
Chiara Parravicini, Graziella Ranghino, Maria P. A...
BMCBI
2006
112views more  BMCBI 2006»
13 years 7 months ago
Assessment of the relationship between pre-chip and post-chip quality measures for Affymetrix GeneChip expression data
Background: Gene expression microarray experiments are expensive to conduct and guidelines for acceptable quality control at intermediate steps before and after the samples are hy...
Lesley Jones, Darlene R. Goldstein, Gareth P. Hugh...
BMCBI
2007
168views more  BMCBI 2007»
13 years 7 months ago
Advancing translational research with the Semantic Web
Background: A fundamental goal of the U.S. National Institute of Health (NIH) "Roadmap" is to strengthen Translational Research, defined as the movement of discoveries i...
Alan Ruttenberg, Tim Clark, William Bug, Matthias ...
EXPERT
2007
109views more  EXPERT 2007»
13 years 7 months ago
Mexar2: AI Solves Mission Planner Problems
s planners work at a higher abstraction level while it performs low-level, often-repetitive tasks. It also helps them produce a plan rapidly, explore alternative solutions, and cho...
Amedeo Cesta, Gabriella Cortellessa, Michel Denis,...
BMCBI
2005
108views more  BMCBI 2005»
13 years 7 months ago
The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymer
Background: The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and t...
François Ferron, Cécile Bussetta, H&...
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