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BMCBI
2007
134views more  BMCBI 2007»
13 years 8 months ago
A framework for significance analysis of gene expression data using dimension reduction methods
Background: The most popular methods for significance analysis on microarray data are well suited to find genes differentially expressed across predefined categories. However, ide...
Lars Halvor Gidskehaug, Endre Anderssen, Arnar Fla...
BMCBI
2007
158views more  BMCBI 2007»
13 years 8 months ago
MetaLook: a 3D visualisation software for marine ecological genomics
Background: Marine ecological genomics can be defined as the application of genomic sciences to understand the structure and function of marine ecosystems. In this field of resear...
Thierry Lombardot, Renzo Kottmann, Gregory Giulian...
BMCBI
2010
129views more  BMCBI 2010»
13 years 8 months ago
Geoseq: a tool for dissecting deep-sequencing datasets
Background: Datasets generated on deep-sequencing platforms have been deposited in various public repositories such as the Gene Expression Omnibus (GEO), Sequence Read Archive (SR...
James Gurtowski, Anthony Cancio, Hardik Shah, Chay...
BMCBI
2007
157views more  BMCBI 2007»
13 years 8 months ago
Impact of image segmentation on high-content screening data quality for SK-BR-3 cells
Background: High content screening (HCS) is a powerful method for the exploration of cellular signalling and morphology that is rapidly being adopted in cancer research. HCS uses ...
Andrew A. Hill, Peter LaPan, Yizheng Li, Steve Han...
BMCBI
2008
121views more  BMCBI 2008»
13 years 8 months ago
Stability of gene contributions and identification of outliers in multivariate analysis of microarray data
Background: Multivariate ordination methods are powerful tools for the exploration of complex data structures present in microarray data. These methods have several advantages com...
Florent Baty, Daniel Jaeger, Frank Preiswerk, Mart...