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BMCBI
2010
131views more  BMCBI 2010»
13 years 9 months ago
FACT: Functional annotation transfer between proteins with similar feature architectures
Background: The increasing number of sequenced genomes provides the basis for exploring the genetic and functional diversity within the tree of life. Only a tiny fraction of the e...
Tina Koestler, Arndt von Haeseler, Ingo Ebersberge...
BMCBI
2007
160views more  BMCBI 2007»
13 years 9 months ago
Identifying protein complexes directly from high-throughput TAP data with Markov random fields
Background: Predicting protein complexes from experimental data remains a challenge due to limited resolution and stochastic errors of high-throughput methods. Current algorithms ...
Wasinee Rungsarityotin, Roland Krause, Arno Sch&ou...
BMCBI
2008
163views more  BMCBI 2008»
13 years 9 months ago
The Annotation, Mapping, Expression and Network (AMEN) suite of tools for molecular systems biology
Background: High-throughput genome biological experiments yield large and multifaceted datasets that require flexible and user-friendly analysis tools to facilitate their interpre...
Frédéric Chalmel, Michael Primig
BMCBI
2006
101views more  BMCBI 2006»
13 years 9 months ago
Hierarchical modularity of nested bow-ties in metabolic networks
Background: The exploration of the structural topology and the organizing principles of genomebased large-scale metabolic networks is essential for studying possible relations bet...
Jing Zhao, Hong Yu, Jianhua Luo, Zhi-Wei Cao, Yi-X...
BMCBI
2006
157views more  BMCBI 2006»
13 years 9 months ago
Comparison of protein interaction networks reveals species conservation and divergence
Background: Recent progresses in high-throughput proteomics have provided us with a first chance to characterize protein interaction networks (PINs), but also raised new challenge...
Zhi Liang, Meng Xu, Maikun Teng, Liwen Niu