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» Extensions to gene set enrichment
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BMCBI
2010
277views more  BMCBI 2010»
13 years 10 months ago
PCA2GO: a new multivariate statistics based method to identify highly expressed GO-Terms
Background: Several tools have been developed to explore and search Gene Ontology (GO) databases allowing efficient GO enrichment analysis and GO tree visualization. Nevertheless,...
Marc Bruckskotten, Mario Looso, Franz Cemic, Anne ...
BMCBI
2005
113views more  BMCBI 2005»
13 years 9 months ago
Pathway level analysis of gene expression using singular value decomposition
Background: A promising direction in the analysis of gene expression focuses on the changes in expression of specific predefined sets of genes that are known in advance to be rela...
John K. Tomfohr, Jun Lu, Thomas B. Kepler
BMCBI
2010
116views more  BMCBI 2010»
13 years 10 months ago
FiGS: a filter-based gene selection workbench for microarray data
Background: The selection of genes that discriminate disease classes from microarray data is widely used for the identification of diagnostic biomarkers. Although various gene sel...
Taeho Hwang, Choong-Hyun Sun, Taegyun Yun, Gwan-Su...
BMCBI
2005
114views more  BMCBI 2005»
13 years 9 months ago
Extension of Lander-Waterman theory for sequencing filtered DNA libraries
Background: The degree to which conventional DNA sequencing techniques will be successful for highly repetitive genomes is unclear. Investigators are therefore considering various...
Michael C. Wendl, W. Bradley Barbazuk
BMCBI
2007
131views more  BMCBI 2007»
13 years 10 months ago
On the detection of functionally coherent groups of protein domains with an extension to protein annotation
Background: Protein domains coordinate to perform multifaceted cellular functions, and domain combinations serve as the functional building blocks of the cell. The available metho...
William A. McLaughlin, Ken Chen, Tingjun Hou, Wei ...