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» Extensions to gene set enrichment
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RECOMB
2005
Springer
14 years 10 months ago
Causal Inference of Regulator-Target Pairs by Gene Mapping of Expression Phenotypes
Background: Correlations between polymorphic markers and observed phenotypes provide the basis for mapping traits in quantitative genetics. When the phenotype is gene expression, ...
David Kulp, Manjunatha Jagalur
NAR
2010
111views more  NAR 2010»
13 years 4 months ago
Babelomics: an integrative platform for the analysis of transcriptomics, proteomics and genomic data with advanced functional pr
Babelomics is a response to the growing necessity of integrating and analyzing different types of genomic data in an environment that allows an easy functional interpretation of t...
Ignacio Medina, José Carbonell, Luis Pulido...
TKDE
2008
127views more  TKDE 2008»
13 years 9 months ago
Maximal Subspace Coregulated Gene Clustering
Clustering is a popular technique for analyzing microarray data sets, with n genes and m experimental conditions. As explored by biologists, there is a real need to identify coregu...
Yuhai Zhao, Jeffrey Xu Yu, Guoren Wang, Lei Chen 0...
BMCBI
2006
127views more  BMCBI 2006»
13 years 10 months ago
Using local gene expression similarities to discover regulatory binding site modules
Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...
BMCBI
2008
135views more  BMCBI 2008»
13 years 10 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...