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» Extensions to gene set enrichment
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BMCBI
2010
101views more  BMCBI 2010»
13 years 10 months ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...
NAR
2007
155views more  NAR 2007»
13 years 9 months ago
AthaMap web tools for the analysis and identification of co-regulated genes
The AthaMap database generates a map of cisregulatory elements for the whole Arabidopsis thaliana genome. This database has been extended by new tools to identify common cis-regul...
Claudia Galuschka, Martin Schindler, Lorenz Bü...
BMCBI
2011
13 years 4 months ago
Statistical Test of Expression Pattern (STEPath): a new strategy to integrate gene expression data with genomic information in i
Background: In the last decades, microarray technology has spread, leading to a dramatic increase of publicly available datasets. The first statistical tools developed were focuse...
Paolo G. V. Martini, Davide Risso, Gabriele Sales,...
JBI
2011
283views Bioinformatics» more  JBI 2011»
13 years 4 months ago
Cross-product extensions of the Gene Ontology
The Gene Ontology is being normalized and extended to include computable logical definitions. These definitions are partitioned into mutually exclusive cross-product sets, many of...
Christopher J. Mungall, Michael Bada, Tanya Z. Ber...
RECOMB
2008
Springer
14 years 10 months ago
Detecting Disease-Specific Dysregulated Pathways Via Analysis of Clinical Expression Profiles
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
Igor Ulitsky, Richard M. Karp, Ron Shamir