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BMCBI
2008
117views more  BMCBI 2008»
13 years 9 months ago
New resampling method for evaluating stability of clusters
Background: Hierarchical clustering is a widely applied tool in the analysis of microarray gene expression data. The assessment of cluster stability is a major challenge in cluste...
Irina Gana Dresen, Tanja Boes, Johannes Hüsin...
BMCBI
2006
113views more  BMCBI 2006»
13 years 9 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
NAR
2006
170views more  NAR 2006»
13 years 8 months ago
The UCSC Genome Browser Database: update 2006
The University of California Santa Cruz Genome Browser Database (GBD) contains sequence and annotation data for the genomes of about a dozen vertebrate species and several major m...
Angela S. Hinrichs, Donna Karolchik, Robert Baerts...
BMCBI
2007
117views more  BMCBI 2007»
13 years 9 months ago
Application of a correlation correction factor in a microarray cross-platform reproducibility study
Background: Recent research examining cross-platform correlation of gene expression intensities has yielded mixed results. In this study, we demonstrate use of a correction factor...
Kellie J. Archer, Catherine I. Dumur, G. Scott Tay...
BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
13 years 9 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...