The recent growth in genomic data and measurements of genome-wide expression patterns allows us to apply computational tools to examine gene regulation by transcription factors. I...
Living cells are the product of gene expression programs that involve the regulated transcription of thousands of genes. The elucidation of transcriptional regulatory networks in ...
Clustering has been one of the most popular methods to discover useful biological insights from DNA microarray. An interesting paradigm is simultaneous clustering of both genes an...
Recent studies (Alizadeh et al, [1]; Bittner et al,[5]; Golub et al, [11]) demonstrate the discovery of putative disease subtypes from gene expression data. The underlying computa...
Learning the structure of a gene regulatory network from time-series gene expression data is a significant challenge. Most approaches proposed in the literature to date attempt to ...