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» Extracting active pathways from gene expression data
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BMCBI
2007
126views more  BMCBI 2007»
13 years 7 months ago
Comparison of gene expression profiles altered by comfrey and riddelliine in rat liver
Background: Comfrey (Symphytum officinale) is a perennial plant and has been consumed by humans as a vegetable, a tea and an herbal medicine for more than 2000 years. It, however,...
Lei Guo, Nan Mei, Stacey L. Dial, James C. Fuscoe,...
LREC
2008
166views Education» more  LREC 2008»
13 years 9 months ago
KnoFusius: a New Knowledge Fusion System for Interpretation of Gene Expression Data
This paper introduces a new architecture that aims at combining molecular biology data with information automatically extracted from scientific literature (using text mining techn...
Pavel Smrz
BIBE
2003
IEEE
121views Bioinformatics» more  BIBE 2003»
14 years 28 days ago
Time Series Analysis of Gene Expression and Location Data
We develop a method for integrating time series expression profiles and factor-gene binding data to quantify dynamic aspects of gene regulation. We estimate latencies for transcr...
Chen-Hsiang Yeang, Tommi Jaakkola
BMCBI
2007
174views more  BMCBI 2007»
13 years 7 months ago
Inferring activity changes of transcription factors by binding association with sorted expression profiles
Background: The identification of transcription factors (TFs) associated with a biological process is fundamental to understanding its regulatory mechanisms. From microarray data,...
Chao Cheng, Xiting Yan, Fengzhu Sun, Lei M. Li
BMCBI
2011
12 years 11 months ago
Reconstructing genome-wide regulatory network of E. coli using transcriptome data and predicted transcription factor activities
Background: Gene regulatory networks play essential roles in living organisms to control growth, keep internal metabolism running and respond to external environmental changes. Un...
Yao Fu, Laura R. Jarboe, Julie A. Dickerson