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» Extracting active pathways from gene expression data
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BMCBI
2008
128views more  BMCBI 2008»
13 years 7 months ago
In silico analysis of expressed sequence tags from Trichostrongylus vitrinus (Nematoda): comparison of the automated ESTExplorer
Background: The analysis of expressed sequence tags (EST) offers a rapid and cost effective approach to elucidate the transcriptome of an organism, but requires several computatio...
Shivashankar H. Nagaraj, Robin B. Gasser, Alasdair...
BMCBI
2007
123views more  BMCBI 2007»
13 years 7 months ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
NAR
2008
174views more  NAR 2008»
13 years 6 months ago
miRGator: an integrated system for functional annotation of microRNAs
MicroRNAs (miRNAs) constitute an important class of regulators that are involved in various cellular and disease processes. However, the functional significance of each miRNA is m...
Seungyoon Nam, Bumjin Kim, Seokmin Shin, Sanghyuk ...
TSMC
2008
136views more  TSMC 2008»
13 years 7 months ago
Learning Relational Descriptions of Differentially Expressed Gene Groups
Abstract-- This paper presents a method that uses gene ontologies, together with the paradigm of relational subgroup discovery, to find compactly described groups of genes differen...
Igor Trajkovski, Filip Zelezný, Nada Lavrac...
NAR
2007
135views more  NAR 2007»
13 years 7 months ago
g: Profiler - a web-based toolset for functional profiling of gene lists from large-scale experiments
g:Profiler (http://biit.cs.ut.ee/gprofiler/) is a public web server for characterising and manipulating gene lists resulting from mining high-throughput genomic data. g:Profiler h...
Jüri Reimand, Meelis Kull, Hedi Peterson, Jaa...