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» Extracting active pathways from gene expression data
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BIBM
2009
IEEE
151views Bioinformatics» more  BIBM 2009»
14 years 3 months ago
Detection of Gene Orthology Based on Protein-Protein Interaction Networks
Abstract—Ortholog detection methods present a powerful approach for finding genes that participate in similar biological processes across different organisms, extending our unde...
Fadi Towfic, M. Heather West Greenlee, Vasant Hona...
NAR
2011
227views Computer Vision» more  NAR 2011»
12 years 11 months ago
CADgene: a comprehensive database for coronary artery disease genes
Coronary artery disease (CAD) is a complex, multifactorial disease and a leading cause of mortality world wide. Over the past decades, great efforts have been made to elucidate th...
Hui Liu, Wei Liu, Yifang Liao, Long Cheng, Qian Li...
BMCBI
2008
157views more  BMCBI 2008»
13 years 9 months ago
Dimension reduction with redundant gene elimination for tumor classification
Background: Analysis of gene expression data for tumor classification is an important application of bioinformatics methods. But it is hard to analyse gene expression data from DN...
Xue-Qiang Zeng, Guo-Zheng Li, Jack Y. Yang, Mary Q...
ISBI
2011
IEEE
13 years 16 days ago
Automated lineage tree reconstruction from Caenorhabditis elegans image data using particle filtering based cell tracking
Caenorhabditis elegans is an important model organism for the study of molecular mechanisms of development and disease processes, due to its well-known genome and invariant cell l...
Noemí Carranza-Herrezuelo, Ihor Smal, Oleh ...
BMCBI
2010
110views more  BMCBI 2010»
13 years 9 months ago
Towards the systematic discovery of signal transduction networks using phosphorylation dynamics data
Background: Phosphorylation is a ubiquitous and fundamental regulatory mechanism that controls signal transduction in living cells. The number of identified phosphoproteins and th...
Haruna Imamura, Nozomu Yachie, Rintaro Saito, Yasu...