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BMCBI
2010
167views more  BMCBI 2010»
13 years 11 months ago
Inference of sparse combinatorial-control networks from gene-expression data: a message passing approach
Background: Transcriptional gene regulation is one of the most important mechanisms in controlling many essential cellular processes, including cell development, cell-cycle contro...
Marc Bailly-Bechet, Alfredo Braunstein, Andrea Pag...
BMCBI
2007
126views more  BMCBI 2007»
13 years 10 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
SCFBM
2008
151views more  SCFBM 2008»
13 years 10 months ago
Wndchrm - an open source utility for biological image analysis
Background: Biological imaging is an emerging field, covering a wide range of applications in biological and clinical research. However, while machinery for automated experimentin...
Lior Shamir, Nikita Orlov, D. Mark Eckley, Tomasz ...
BMCBI
2008
167views more  BMCBI 2008»
13 years 11 months ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren
JCB
2008
159views more  JCB 2008»
13 years 10 months ago
BayesMD: Flexible Biological Modeling for Motif Discovery
We present BayesMD, a Bayesian Motif Discovery model with several new features. Three different types of biological a priori knowledge are built into the framework in a modular fa...
Man-Hung Eric Tang, Anders Krogh, Ole Winther