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BMCBI
2011
13 years 2 months ago
Support vector machines-based identification of alternative splicing in Arabidopsis thaliana from whole-genome tiling arrays
Background: Alternative splicing (AS) is a process which generates several distinct mRNA isoforms from the same gene by splicing different portions out of the precursor transcript...
Johannes Eichner, Georg Zeller, Sascha Laubinger, ...
BMCBI
2006
170views more  BMCBI 2006»
13 years 7 months ago
Biclustering of gene expression data by non-smooth non-negative matrix factorization
Background: The extended use of microarray technologies has enabled the generation and accumulation of gene expression datasets that contain expression levels of thousands of gene...
Pedro Carmona-Saez, Roberto D. Pascual-Marqui, Fra...
BMCBI
2007
148views more  BMCBI 2007»
13 years 7 months ago
Evaluation of gene-expression clustering via mutual information distance measure
Background: The definition of a distance measure plays a key role in the evaluation of different clustering solutions of gene expression profiles. In this empirical study we compa...
Ido Priness, Oded Maimon, Irad E. Ben-Gal
BMCBI
2007
135views more  BMCBI 2007»
13 years 7 months ago
Measuring similarities between gene expression profiles through new data transformations
Background: Clustering methods are widely used on gene expression data to categorize genes with similar expression profiles. Finding an appropriate (dis)similarity measure is crit...
Kyungpil Kim, Shibo Zhang, Keni Jiang, Li Cai, In-...
BICOB
2009
Springer
13 years 5 months ago
A Biclustering Method to Discover Co-regulated Genes Using Diverse Gene Expression Datasets
We propose a two-step biclustering approach to mine co-regulation patterns of a given reference gene to discover other genes that function in a common biological process. Currently...
Doruk Bozdag, Jeffrey D. Parvin, Ümit V. &Cce...