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BMCBI
2010
243views more  BMCBI 2010»
13 years 9 months ago
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data
Background: Visualization of DNA microarray data in two or three dimensional spaces is an important exploratory analysis step in order to detect quality issues or to generate new ...
Christoph Bartenhagen, Hans-Ulrich Klein, Christia...
BMCBI
2006
119views more  BMCBI 2006»
13 years 9 months ago
LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Guoli Wang, Andrew V. Kossenkov, Michael F. Ochs
BMCBI
2006
153views more  BMCBI 2006»
13 years 9 months ago
Cancer diagnosis marker extraction for soft tissue sarcomas based on gene expression profiling data by using projective adaptive
Background: Recent advances in genome technologies have provided an excellent opportunity to determine the complete biological characteristics of neoplastic tissues, resulting in ...
Hiro Takahashi, Takeshi Nemoto, Teruhiko Yoshida, ...
BMCBI
2007
152views more  BMCBI 2007»
13 years 9 months ago
Difference-based clustering of short time-course microarray data with replicates
Background: There are some limitations associated with conventional clustering methods for short time-course gene expression data. The current algorithms require prior domain know...
Jihoon Kim, Ju Han Kim
BMCBI
2007
143views more  BMCBI 2007»
13 years 9 months ago
Gene selection for classification of microarray data based on the Bayes error
Background: With DNA microarray data, selecting a compact subset of discriminative genes from thousands of genes is a critical step for accurate classification of phenotypes for, ...
Ji-Gang Zhang, Hong-Wen Deng