Background: Genetic regulatory networks (GRN) can be described by differential equations with SUM logic which has been found in many natural systems. Identification of the network...
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...
Background: It is thought that genes with similar patterns of mRNA expression and genes with similar functions are likely to be regulated via the same mechanisms. It has been diff...
Dominic J. Allocco, Isaac S. Kohane, Atul J. Butte
Background: Gene expression microarray and other multiplex data hold promise for addressing the challenges of cellular complexity, refined diagnoses and the discovery of well-targ...
Abdallah Sayyed-Ahmad, Kagan Tuncay, Peter J. Orto...
Background: Eukaryotic cells have developed mechanisms to respond to external environmental or physiological changes (stresses). In order to increase the activities of stress-prot...