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» Family pairwise search with embedded motif models
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GCB
2009
Springer
105views Biometrics» more  GCB 2009»
14 years 2 months ago
Maximum Likelihood Estimation of Weight Matrices for Targeted Homology Search
: Genome annotation relies to a large extent on the recognition of homologs to already known genes. The starting point for such protocols is a collection of known sequences from on...
Peter Menzel, Jan Gorodkin, Peter F. Stadler
CCECE
2006
IEEE
14 years 1 months ago
Evaluation of RNA Secondary Structure Motifs using Regression Analysis
Recent experimental evidences have shown that ribonucleic acid (RNA) plays a greater role in the cell than previously thought. An ensemble of RNA sequences believed to contain sig...
Mohammad Anwar, Marcel Turcotte
NIPS
2004
13 years 9 months ago
Euclidean Embedding of Co-Occurrence Data
Embedding algorithms search for low dimensional structure in complex data, but most algorithms only handle objects of a single type for which pairwise distances are specified. Thi...
Amir Globerson, Gal Chechik, Fernando C. Pereira, ...
BMCBI
2002
133views more  BMCBI 2002»
13 years 7 months ago
Identification and characterization of subfamily-specific signatures in a large protein superfamily by a hidden Markov model app
Background: Most profile and motif databases strive to classify protein sequences into a broad spectrum of protein families. The next step of such database studies should include ...
Kevin Truong, Mitsuhiko Ikura
BMCBI
2011
12 years 11 months ago
GPCR-SSFE: A comprehensive database of G-protein-coupled receptor template predictions and homology models
Background: G protein-coupled receptors (GPCRs) transduce a wide variety of extracellular signals to within the cell and therefore have a key role in regulating cell activity and ...
Catherine L. Worth, Annika Kreuchwig, Gunnar Klein...