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» Family pairwise search with embedded motif models
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BMCBI
2010
105views more  BMCBI 2010»
13 years 7 months ago
Subdivision of the MDR superfamily of medium-chain dehydrogenases/reductases through iterative hidden Markov model refinement
Background: The Medium-chain Dehydrogenases/Reductases (MDR) form a protein superfamily whose size and complexity defeats traditional means of subclassification; it currently has ...
Joel Hedlund, Hans Jörnvall, Bengt Persson
NAR
2002
80views more  NAR 2002»
13 years 7 months ago
PRINTS and PRINTS-S shed light on protein ancestry
The PRINTS database houses a collection of protein fingerprints. These may be used to make family and tentative functional assignments for uncharacterised sequences. The September...
Terri K. Attwood, Martin J. Blythe, Darren R. Flow...
BMCBI
2005
132views more  BMCBI 2005»
13 years 7 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
JCB
2002
116views more  JCB 2002»
13 years 7 months ago
A Novel Approach to Remote Homology Detection: Jumping Alignments
We describe a new algorithm for protein classi cation and the detection of remote homologs. The rationale is to exploit both vertical and horizontal information of a multiple alig...
Rainer Spang, Marc Rehmsmeier, Jens Stoye
SDM
2009
SIAM
161views Data Mining» more  SDM 2009»
14 years 4 months ago
Polynomial-Delay and Polynomial-Space Algorithms for Mining Closed Sequences, Graphs, and Pictures in Accessible Set Systems.
In this paper, we study efficient closed pattern mining in a general framework of set systems, which are families of subsets ordered by set-inclusion with a certain structure, pro...
Hiroki Arimura, Takeaki Uno