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JCC
2011
154views more  JCC 2011»
12 years 11 months ago
Can we trust docking results? Evaluation of seven commonly used programs on PDBbind database
: Docking is one of the most commonly used techniques in drug design. It is used for both identifying correct poses of a ligand in the binding site of a protein as well as for the ...
Dariusz Plewczynski, Michal Lazniewski, Rafal Augu...
BMCBI
2002
133views more  BMCBI 2002»
13 years 8 months ago
Identification and characterization of subfamily-specific signatures in a large protein superfamily by a hidden Markov model app
Background: Most profile and motif databases strive to classify protein sequences into a broad spectrum of protein families. The next step of such database studies should include ...
Kevin Truong, Mitsuhiko Ikura
ICML
2002
IEEE
14 years 9 months ago
Learning the Kernel Matrix with Semi-Definite Programming
Kernel-based learning algorithms work by embedding the data into a Euclidean space, and then searching for linear relations among the embedded data points. The embedding is perfor...
Gert R. G. Lanckriet, Nello Cristianini, Peter L. ...
SIGIR
2003
ACM
14 years 1 months ago
Domain-independent text segmentation using anisotropic diffusion and dynamic programming
This paper presents a novel domain-independent text segmentation method, which identifies the boundaries of topic changes in long text documents and/or text streams. The method c...
Xiang Ji, Hongyuan Zha
BMCBI
2010
151views more  BMCBI 2010»
13 years 8 months ago
Using diffusion distances for flexible molecular shape comparison
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
Yu-Shen Liu, Qi Li, Guo-Qin Zheng, Karthik Ramani,...