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JCC
2010
105views more  JCC 2010»
13 years 6 months ago
Fast determination of the optimal rotational matrix for macromolecular superpositions
: Finding the rotational matrix that minimizes the sum of squared deviations between two vectors is an important problem in bioinformatics and crystallography. Traditional algorith...
Pu Liu, Dimitris K. Agrafiotis, Douglas L. Theobal...
NAR
2006
164views more  NAR 2006»
13 years 7 months ago
FISH - family identification of sequence homologues using structure anchored hidden Markov models
The FISH server is highly accurate in identifying the family membership of domains in a query protein sequence, even in the case of very low sequence identities to known homologue...
Jeanette Tångrot, Lixiao Wang, Bo Kågs...
RECOMB
2003
Springer
14 years 7 months ago
Accurate detection of very sparse sequence motifs
Protein sequence alignments are more reliable the shorter the evolutionary distance. Here, we align distantly related proteins using many closely spaced intermediate sequences as ...
Andreas Heger, Michael Lappe, Liisa Holm
BMCBI
2004
77views more  BMCBI 2004»
13 years 7 months ago
A structural study for the optimisation of functional motifs encoded in protein sequences
Background: A large number of PROSITE patterns select false positives and/or miss known true positives. It is possible that
Allegra Via, Manuela Helmer-Citterich
CIBCB
2005
IEEE
14 years 1 months ago
Toward Protein Structure Analysis with Self-Organizing Maps
- Establishing structure-function relationships on the proteomic scale is a unique challenge faced by bioinformatics and molecular biosciences. Large protein families represent nat...
Lutz Hamel, Gongqin Sun, Jing Zhang