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» Fast Structured Motif Search in DNA Sequences
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SDM
2009
SIAM
164views Data Mining» more  SDM 2009»
14 years 4 months ago
Exact Discovery of Time Series Motifs.
Time series motifs are pairs of individual time series, or subsequences of a longer time series, which are very similar to each other. As with their discrete analogues in computat...
Abdullah Mueen, Eamonn J. Keogh, M. Brandon Westov...
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
MOTIPS: Automated Motif Analysis for Predicting Targets of Modular Protein Domains
Background: Many protein interactions, especially those involved in signaling, involve short linear motifs consisting of 5-10 amino acid residues that interact with modular protei...
Hugo Y. K. Lam, Philip M. Kim, Janine Mok, Raffi T...
BMCBI
2002
108views more  BMCBI 2002»
13 years 7 months ago
A memory-efficient dynamic programming algorithm for optimal alignment of a sequence to an RNA secondary structure
Background: Covariance models (CMs) are probabilistic models of RNA secondary structure, analogous to profile hidden Markov models of linear sequence. The dynamic programming algo...
Sean R. Eddy
SAC
2010
ACM
13 years 7 months ago
FANGS: high speed sequence mapping for next generation sequencers
Next Generation Sequencing machines are generating millions of short DNA sequences (reads) everyday. There is a need for efficient algorithms to map these sequences to the referen...
Sanchit Misra, Ramanathan Narayanan, Simon Lin, Al...
ICSM
2007
IEEE
14 years 1 months ago
A Maintainable Software Architecture for Fast and Modular Bioinformatics Sequence Search
Bioinformaticists use the Basic Local Alignment Search Tool (BLAST) to characterize an unknown sequence by comparing it against a database of known sequences, thus detecting evolu...
Jeremy S. Archuleta, Eli Tilevich, Wu-chun Feng