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» Fast Structured Motif Search in DNA Sequences
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BMCBI
2005
122views more  BMCBI 2005»
13 years 7 months ago
A neural strategy for the inference of SH3 domain-peptide interaction specificity
Background: The SH3 domain family is one of the most representative and widely studied cases of so-called Peptide Recognition Modules (PRM). The polyproline II motif PxxP that gen...
Enrico Ferraro, Allegra Via, Gabriele Ausiello, Ma...
DASFAA
2005
IEEE
209views Database» more  DASFAA 2005»
14 years 1 months ago
PADS: Protein Structure Alignment Using Directional Shape Signatures
A novel approach for similarity search on the protein structure databases is proposed. PADS (Protein Alignment by Directional shape Signatures) incorporates the three dimensional ...
S. Alireza Aghili, Divyakant Agrawal, Amr El Abbad...
CC
2008
Springer
13 years 9 months ago
Generating SIMD Vectorized Permutations
Abstract. This paper introduces a method to generate efficient vectorized implementations of small stride permutations using only vector load and vector shuffle instructions. These...
Franz Franchetti, Markus Püschel
23
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ICCAD
2009
IEEE
147views Hardware» more  ICCAD 2009»
13 years 5 months ago
SAT-based protein design
Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
Noah Ollikainen, Ellen Sentovich, Carlos Coelho, A...
BMCBI
2008
200views more  BMCBI 2008»
13 years 7 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia