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BMCBI
2010
15 years 2 months ago
2010
Background: Mass spectrometry (MS) is an essential analytical tool in proteomics. Many existing algorithms for peptide detection are based on isotope template matching and usually...
131
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BMCBI
2007
15 years 2 months ago
2007
Background: Innovative extensions of (M) ANOVA gain common ground for the analysis of designed metabolomics experiments. ASCA is such a multivariate analysis method; it has succes...
117
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BMCBI
2010
15 years 2 months ago
2010
Background: The occurrence of a genetic bottleneck in HIV sexual or mother-to-infant transmission has been well documented. This results in a majority of new infections being homo...
BMCBI
2008
15 years 2 months ago
2008
Background: In real-time quantitative PCR studies using absolute plasmid DNA standards, a calibration curve is developed to estimate an unknown DNA concentration. However, potenti...
157
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BMCBI
2008
15 years 2 months ago
2008
Background: Identification of differentially expressed genes is a typical objective when analyzing gene expression data. Recently, Bayesian hierarchical models have become increas...