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BMCBI
2010
13 years 9 months ago
2010
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
BMCBI
2008
13 years 9 months ago
2008
Background: A major obstacle in treatment of HIV is the ability of the virus to mutate rapidly into drug-resistant variants. A method for predicting the susceptibility of mutated ...
BMCBI
2010
13 years 9 months ago
2010
Background: In biological and medical domain, the use of web services made the data and computation functionality accessible in a unified manner, which helped automate the data pi...
BMCBI
2007
13 years 9 months ago
2007
Background: Analyzing differential-gene-expression data in the context of protein-interaction networks (PINs) yields information on the functional cellular status. PINs can be for...
BMCBI
2008
13 years 9 months ago
2008
Background: Reliable prediction of antibody, or B-cell, epitopes remains challenging yet highly desirable for the design of vaccines and immunodiagnostics. A correlation between a...