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BMCBI
2004
146views more  BMCBI 2004»
13 years 7 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
ISBRA
2010
Springer
13 years 6 months ago
Analysis of Gene Interactions Using Restricted Boolean Networks and Time-Series Data
A popular model for gene regulatory networks is the Boolean network model. In this paper, we propose an algorithm to perform an analysis of gene regulatory interactions using the B...
Carlos H. A. Higa, Vitor H. P. Louzada, Ronaldo Fu...
RECOMB
2004
Springer
14 years 8 months ago
Modeling and Analysis of Heterogeneous Regulation in Biological Networks
Abstract. In this study we propose a novel model for the representation of biological networks and provide algorithms for learning model parameters from experimental data. Our appr...
Irit Gat-Viks, Amos Tanay, Ron Shamir
EUROGP
2006
Springer
140views Optimization» more  EUROGP 2006»
13 years 11 months ago
Evolving Noisy Oscillatory Dynamics in Genetic Regulatory Networks
We introduce a genetic programming (GP) approach for evolving genetic networks that demonstrate desired dynamics when simulated as a discrete stochastic process. Our representation...
André Leier, P. Dwight Kuo, Wolfgang Banzha...
BIOSYSTEMS
2007
115views more  BIOSYSTEMS 2007»
13 years 7 months ago
Evolving fuzzy rules to model gene expression
This paper develops an algorithm that extracts explanatory rules from microarray data, which we treat as time series, using genetic programming (GP) and fuzzy logic. Reverse polis...
Ricardo Linden, Amit Bhaya