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BMCBI
2004
135views more  BMCBI 2004»
13 years 6 months ago
Information assessment on predicting protein-protein interactions
Background: Identifying protein-protein interactions is fundamental for understanding the molecular machinery of the cell. Proteome-wide studies of protein-protein interactions ar...
Nan Lin, Baolin Wu, Ronald Jansen, Mark Gerstein, ...
BMCBI
2011
12 years 10 months ago
Detection of Lineage-Specific Evolutionary Changes among Primate Species
Background: Comparison of the human genome with other primates offers the opportunity to detect evolutionary events that created the diverse phenotypes among the primate species. ...
Mihaela Pertea, Geo Pertea, Steven L. Salzberg
BMCBI
2007
152views more  BMCBI 2007»
13 years 7 months ago
Bioinformatic identification of novel putative photoreceptor specific cis-elements
Background: Cell specific gene expression is largely regulated by different combinations of transcription factors that bind cis-elements in the upstream promoter sequence. However...
Charles G. Danko, Vera A. McIlvain, Maochun Qin, B...
RECOMB
2005
Springer
14 years 7 months ago
An Interaction-Dependent Model for Transcription Factor Binding
Transcriptional regulation is accomplished by several transcription factor proteins that bind to specific DNA elements in the relative vicinity of the gene, and interact with each ...
Li-San Wang, Shane T. Jensen, Sridhar Hannenhalli
BMCBI
2005
109views more  BMCBI 2005»
13 years 7 months ago
Genome comparison without alignment using shortest unique substrings
Background: Sequence comparison by alignment is a fundamental tool of molecular biology. In this paper we show how a number of sequence comparison tasks, including the detection o...
Bernhard Haubold, Nora Pierstorff, Friedrich M&oum...