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BMCBI
2005
133views more  BMCBI 2005»
13 years 7 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
BMCBI
2002
76views more  BMCBI 2002»
13 years 7 months ago
The SGS3 protein involved in PTGS finds a family
Background: Post transcriptional gene silencing (PTGS) is a recently discovered phenomenon that is an area of intense research interest. Components of the PTGS machinery are being...
Alex Bateman
ISDA
2009
IEEE
14 years 2 months ago
MAHATMA: A Genetic Programming-Based Tool for Protein Classification
Proteins can be grouped into families according to some features such as hydrophobicity, composition or structure, aiming to establish common biological functions. This paper pres...
Denise Fukumi Tsunoda, Alex Alves Freitas, Heitor ...
BMCBI
2006
107views more  BMCBI 2006»
13 years 7 months ago
A reinforced merging methodology for mapping unique peptide motifs in members of protein families
Background: Members of a protein family often have highly conserved sequences; most of these sequences carry identical biological functions and possess similar three-dimensional (...
Hao-Teng Chang, Tun-Wen Pai, Tan-Chi Fan, Bo-Han S...
BMCBI
2008
140views more  BMCBI 2008»
13 years 7 months ago
Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Kazutaka Katoh, Hiroyuki Toh