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BMCBI
2007
124views more  BMCBI 2007»
13 years 7 months ago
Analysis on multi-domain cooperation for predicting protein-protein interactions
Background: Domains are the basic functional units of proteins. It is believed that protein-protein interactions are realized through domain interactions. Revealing multi-domain c...
Rui-Sheng Wang, Yong Wang, Ling-Yun Wu, Xiang-Sun ...
BMCBI
2008
242views more  BMCBI 2008»
13 years 7 months ago
New time-scale criteria for model simplification of bio-reaction systems
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
Junwon Choi, Kyung-won Yang, Tai-yong Lee, Sang Yu...
BMCBI
2007
141views more  BMCBI 2007»
13 years 7 months ago
HeliCis: a DNA motif discovery tool for colocalized motif pairs with periodic spacing
Background: Correct temporal and spatial gene expression during metazoan development relies on combinatorial interactions between different transcription factors. As a consequence...
Erik Larsson, Per Lindahl, Petter Mostad
BMCBI
2007
97views more  BMCBI 2007»
13 years 7 months ago
SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets
Background: Array comparative genome hybridization (aCGH) provides information about genomic aberrations. Alterations in the DNA copy number may cause the cell to malfunction, lea...
Carmen Lai, Hugo M. Horlings, Marc J. van de Vijve...
BMCBI
2007
156views more  BMCBI 2007»
13 years 7 months ago
Accuracy of structure-based sequence alignment of automatic methods
Background: Accurate sequence alignments are essential for homology searches and for building three-dimensional structural models of proteins. Since structure is better conserved ...
Changhoon Kim, Byungkook Lee