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BMCBI
2007
144views more  BMCBI 2007»
13 years 8 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...
CIAC
2010
Springer
194views Algorithms» more  CIAC 2010»
14 years 1 months ago
An Algorithmic Framework for Motif Discovery Problems in Weighted Sequences
A weighted sequence is a string in which a set of characters may appear at each position with respective probabilities of occurrence. A common task is to locate a given motif in a ...
Hui Zhang, Qing Guo, Costas S. Iliopoulos
BMCBI
2008
126views more  BMCBI 2008»
13 years 8 months ago
c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
Katerina Kechris, Hao Li
CSB
2003
IEEE
108views Bioinformatics» more  CSB 2003»
14 years 1 months ago
A Pattern Matching Algorithm for Codon Optimization and CpG Motif-Engineering in DNA Expression Vectors
Codon optimization enhances the efficiency of DNA expression vectors used in DNA vaccination and gene therapy by increasing protein expression. Additionally, certain nucleotide mo...
Ravi Vijaya Satya, Amar Mukherjee, Udaykumar Ranga
JCB
2007
108views more  JCB 2007»
13 years 8 months ago
A Dynamic Programming Approach for Finding Common Patterns in RNAs
We developed a dynamic programming approach of computing common sequence structure patterns among two RNAs given their primary sequences and their secondary structures. Common pat...
Sven Siebert, Rolf Backofen