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BMCBI
2007
125views more  BMCBI 2007»
13 years 7 months ago
Statistical tests to compare motif count exceptionalities
Background: Finding over- or under-represented motifs in biological sequences is now a common task in genomics. Thanks to p-value calculation for motif counts, exceptional motifs ...
Stéphane Robin, Sophie Schbath, Vincent Van...
BMCBI
2005
169views more  BMCBI 2005»
13 years 7 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
BMCBI
2010
134views more  BMCBI 2010»
13 years 7 months ago
BayesMotif: de novo protein sorting motif discovery from impure datasets
Background: Protein sorting is the process that newly synthesized proteins are transported to their target locations within or outside of the cell. This process is precisely regul...
Jianjun Hu, Fan Zhang
BMCBI
2008
99views more  BMCBI 2008»
13 years 7 months ago
NestedMICA as an ab initio protein motif discovery tool
Background: Discovering overrepresented patterns in amino acid sequences is an important step in protein functional element identification. We adapted and extended NestedMICA, an ...
Mutlu Dogruel, Thomas A. Down, Tim J. P. Hubbard
ISBRA
2009
Springer
14 years 2 months ago
Mining of cis-Regulatory Motifs Associated with Tissue-Specific Alternative Splicing
KIM, JIHYE. Mining of Cis-Regulatory Motifs Associated with Tissue-Specific Alternative Splicing. (Under the direction of Steffen Heber). Alternative splicing (AS) is an important...
Jihye Kim, Sihui Zhao, Brian E. Howard, Steffen He...