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» Finding Similar Regions in Many Sequences
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BMCBI
2010
189views more  BMCBI 2010»
13 years 7 months ago
High quality protein sequence alignment by combining structural profile prediction and profile alignment using SABERTOOTH
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
Florian Teichert, Jonas Minning, Ugo Bastolla, Mar...
SIGMOD
2004
ACM
144views Database» more  SIGMOD 2004»
14 years 7 months ago
Diamond in the Rough: Finding Hierarchical Heavy Hitters in Multi-Dimensional Data
Data items archived in data warehouses or those that arrive online as streams typically have attributes which take values from multiple hierarchies (e.g., time and geographic loca...
Graham Cormode, Flip Korn, S. Muthukrishnan, Dives...
BIOINFORMATICS
2010
94views more  BIOINFORMATICS 2010»
13 years 7 months ago
Globally, unrelated protein sequences appear random
Motivation: To test whether protein folding constraints and secondary structure sequence preferences significantly reduce the space of amino acid words in proteins, we compared th...
Daniel T. Lavelle, William R. Pearson
ALMOB
2007
155views more  ALMOB 2007»
13 years 7 months ago
Finding coevolving amino acid residues using row and column weighting of mutual information and multi-dimensional amino acid rep
Background: Some amino acid residues functionally interact with each other. This interaction will result in an evolutionary co-variation between these residues – coevolution. Ou...
Rodrigo Gouveia-Oliveira, Anders Gorm Pedersen
APBC
2004
13 years 9 months ago
EMAGEN: An Efficient Approach to Multiple Whole Genome Alignment
Following advances in biotechnology, many new whole genome sequences are becoming available every year. A lot of useful information can be derived from the alignment and compariso...
Jitender S. Deogun, Jingyi Yang, Fangrui Ma