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BMCBI
2007
94views more  BMCBI 2007»
13 years 8 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
BMCBI
2007
77views more  BMCBI 2007»
13 years 8 months ago
Effective selection of informative SNPs and classification on the HapMap genotype data
Background: Since the single nucleotide polymorphisms (SNPs) are genetic variations which determine the difference between any two unrelated individuals, the SNPs can be used to i...
Nina Zhou, Lipo Wang
BMCBI
2007
123views more  BMCBI 2007»
13 years 8 months ago
Robust clustering in high dimensional data using statistical depths
Background: Mean-based clustering algorithms such as bisecting k-means generally lack robustness. Although componentwise median is a more robust alternative, it can be a poor cent...
Yuanyuan Ding, Xin Dang, Hanxiang Peng, Dawn Wilki...
BMCBI
2007
115views more  BMCBI 2007»
13 years 8 months ago
Local comparison of protein structures highlights cases of convergent evolution in analogous functional sites
Background: We performed an exhaustive search for local structural similarities in an ensemble of non-redundant protein functional sites. With the purpose of finding new examples ...
Gabriele Ausiello, Daniele Peluso, Allegra Via, Ma...
IJSNET
2008
118views more  IJSNET 2008»
13 years 8 months ago
Public key cryptography empowered smart dust is affordable
: Public key cryptography (PKC) has been considered for a long time to be computationally too expensive for small battery powered devices. However, PKC turned out to be very benefi...
Steffen Peter, Peter Langendörfer, Krzysztof ...