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» Finding critical backbone structures with genetic algorithms
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BMCBI
2010
178views more  BMCBI 2010»
13 years 6 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...
BMCBI
2005
67views more  BMCBI 2005»
13 years 6 months ago
Selecting additional tag SNPs for tolerating missing data in genotyping
Background: Recent studies have shown that the patterns of linkage disequilibrium observed in human populations have a block-like structure, and a small subset of SNPs (called tag...
Yao-Ting Huang, Kui Zhang, Ting Chen, Kun-Mao Chao
BMCBI
2010
104views more  BMCBI 2010»
13 years 6 months ago
Parameters for accurate genome alignment
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Martin C. Frith, Michiaki Hamada, Paul Horton
ICDE
2007
IEEE
219views Database» more  ICDE 2007»
14 years 8 months ago
Efficient Keyword Search Across Heterogeneous Relational Databases
Keyword search is a familiar and potentially effective way to find information of interest that is "locked" inside relational databases. Current work has generally assum...
Mayssam Sayyadian, Hieu LeKhac, AnHai Doan, Luis G...
ICCAD
2009
IEEE
147views Hardware» more  ICCAD 2009»
13 years 4 months ago
SAT-based protein design
Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
Noah Ollikainen, Ellen Sentovich, Carlos Coelho, A...