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IJBRA
2006
61views more  IJBRA 2006»
13 years 10 months ago
Finding functional promoter motifs by computational methods: a word of caution
: The standard practice in the analysis of promoters is to select promoter regions of convenient length. This may lead to false results when searching for Transcription Factor Bind...
Rajesh Chowdhary, Limsoon Wong, Vladimir B. Bajic
BMCBI
2010
121views more  BMCBI 2010»
13 years 8 months ago
Computing DNA duplex instability profiles efficiently with a two-state model: trends of promoters and binding sites
Background: DNA instability profiles have been used recently for predicting the transcriptional start site and the location of core promoters, and to gain insight into promoter ac...
Miriam R. Kantorovitz, Zoi Rapti, Vladimir Gelev, ...
BMCBI
2007
148views more  BMCBI 2007»
13 years 10 months ago
WeederH: an algorithm for finding conserved regulatory motifs and regions in homologous sequences
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Giulio Pavesi, Federico Zambelli, Graziano Pesole
BMCBI
2008
126views more  BMCBI 2008»
13 years 11 months ago
c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
Katerina Kechris, Hao Li
ISAAC
2004
Springer
125views Algorithms» more  ISAAC 2004»
14 years 4 months ago
Local Gapped Subforest Alignment and Its Application in Finding RNA Structural Motifs
RNA molecules whose secondary structures contain similar substructures often have similar functions. Therefore, an important task in the study of RNA is to develop methods for disc...
Jesper Jansson, Ngo Trung Hieu, Wing-Kin Sung