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BMCBI
2008
71views more  BMCBI 2008»
15 years 6 months ago
A tale of two symmetrical tails: Structural and functional characteristics of palindromes in proteins
Background: It has been previously shown that palindromic sequences are frequently observed in proteins. However, our knowledge about their evolutionary origin and their possible ...
Armita Sheari, Mehdi Kargar, Ali Katanforoush, Sha...
BMCBI
2006
156views more  BMCBI 2006»
15 years 6 months ago
Detecting the limits of regulatory element conservation and divergence estimation using pairwise and multiple alignments
Background: Molecular evolutionary studies of noncoding sequences rely on multiple alignments. Yet how multiple alignment accuracy varies across sequence types, tree topologies, d...
Daniel A. Pollard, Alan M. Moses, Venky N. Iyer, M...
BMCBI
2007
132views more  BMCBI 2007»
15 years 5 months ago
Dependence of paracentric inversion rate on tract length
Background: We develop a Bayesian method based on MCMC for estimating the relative rates of pericentric and paracentric inversions from marker data from two species. The method al...
Thomas L. York, Richard Durrett, Rasmus Nielsen
169
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ML
2008
ACM
101views Machine Learning» more  ML 2008»
15 years 5 months ago
On reoptimizing multi-class classifiers
Significant changes in the instance distribution or associated cost function of a learning problem require one to reoptimize a previously-learned classifier to work under new cond...
Chris Bourke, Kun Deng, Stephen D. Scott, Robert E...
MANSCI
2008
169views more  MANSCI 2008»
15 years 5 months ago
Service Adoption and Pricing of Content Delivery Network (CDN) Services
Content Delivery Networks (CDNs) are a vital component of the Internet's content delivery value chain, servicing nearly a third of the Internet's most popular content si...
Kartik Hosanagar, John C.-I. Chuang, Ramayya Krish...