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» Fixed-Parameter Algorithms in Phylogenetics
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BMCBI
2010
95views more  BMCBI 2010»
13 years 7 months ago
Heuristics for the inversion median problem
Background: The study of genome rearrangements has become a mainstay of phylogenetics and comparative genomics. Fundamental in such a study is the median problem: given three geno...
Vaibhav Rajan, Andrew Wei Xu, Yu Lin, Krister M. S...
BMCBI
2007
107views more  BMCBI 2007»
13 years 7 months ago
Progressive multiple sequence alignments from triplets
Motivation: The quality of progressive sequence alignments strongly depends on the accuracy of the individual pairwise alignment steps since gaps that are introduced at one step c...
Matthias Kruspe, Peter F. Stadler
BMCBI
2007
138views more  BMCBI 2007»
13 years 7 months ago
Fast computation of distance estimators
Background: Some distance methods are among the most commonly used methods for reconstructing phylogenetic trees from sequence data. The input to a distance method is a distance m...
Isaac Elias, Jens Lagergren
BMCBI
2005
138views more  BMCBI 2005»
13 years 7 months ago
Detailed protein sequence alignment based on Spectral Similarity Score (SSS)
Background: The chemical property and biological function of a protein is a direct consequence of its primary structure. Several algorithms have been developed which determine ali...
Kshitiz Gupta, Dina Thomas, S. V. Vidya, K. V. Ven...
BIBM
2007
IEEE
132views Bioinformatics» more  BIBM 2007»
14 years 1 months ago
A Divide-and-Conquer Implementation of Three Sequence Alignment and Ancestor Inference
In this paper, we present an algorithm to simultaneously align three biological sequences with affine gap model and infer their common ancestral sequence. Our algorithm can be fu...
Feng Yue, Jijun Tang