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BMCBI
2008
13 years 7 months ago
2008
Background: Protein secondary structure prediction method based on probabilistic models such as hidden Markov model (HMM) appeals to many because it provides meaningful informatio...
BMCBI
2007
13 years 7 months ago
2007
Background: Protein-protein interactions are critical for cellular functions. Recently developed computational approaches for predicting protein-protein interactions utilize co-ev...
BMCBI
2008
13 years 7 months ago
2008
Background: The accurate detection of differentially expressed (DE) genes has become a central task in microarray analysis. Unfortunately, the noise level and experimental variabi...
BMCBI
2008
13 years 7 months ago
2008
Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...
BMCBI
2008
13 years 7 months ago
2008
To address the challenges of information integration and retrieval, the computational genomics community increasingly has come to rely on the methodology of creating annotations o...