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CIKM
2006
Springer
14 years 2 months ago
Structure-based querying of proteins using wavelets
The ability to retrieve molecules based on structural similarity has use in many applications, from disease diagnosis and treatment to drug discovery and design. In this paper, we...
Keith Marsolo, Srinivasan Parthasarathy, Kotagiri ...
AAAI
2008
14 years 21 days ago
Clustering via Random Walk Hitting Time on Directed Graphs
In this paper, we present a general data clustering algorithm which is based on the asymmetric pairwise measure of Markov random walk hitting time on directed graphs. Unlike tradi...
Mo Chen, Jianzhuang Liu, Xiaoou Tang
BMCBI
2007
163views more  BMCBI 2007»
13 years 10 months ago
A coherent graph-based semantic clustering and summarization approach for biomedical literature and a new summarization evaluati
Background: A huge amount of biomedical textual information has been produced and collected in MEDLINE for decades. In order to easily utilize biomedical information in the free t...
Illhoi Yoo, Xiaohua Hu, Il-Yeol Song
BMCBI
2005
201views more  BMCBI 2005»
13 years 10 months ago
A comparative study of discriminating human heart failure etiology using gene expression profiles
Background: Human heart failure is a complex disease that manifests from multiple genetic and environmental factors. Although ischemic and non-ischemic heart disease present clini...
Xiaohong Huang, Wei Pan, Suzanne Grindle, Xinqiang...
BMCBI
2004
125views more  BMCBI 2004»
13 years 10 months ago
A functional hierarchical organization of the protein sequence space
Background: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patte...
Noam Kaplan, Moriah Friedlich, Menachem Fromer, Mi...