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BMCBI
2008
130views more  BMCBI 2008»
13 years 7 months ago
Function approximation approach to the inference of reduced NGnet models of genetic networks
Background: The inference of a genetic network is a problem in which mutual interactions among genes are deduced using time-series of gene expression patterns. While a number of m...
Shuhei Kimura, Katsuki Sonoda, Soichiro Yamane, Hi...
BMCBI
2007
106views more  BMCBI 2007»
13 years 7 months ago
In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells
Background: Pancreatic beta-cells are the target of an autoimmune attack in type 1 diabetes mellitus (T1DM). This is mediated in part by cytokines, such as interleukin (IL)-1β an...
Najib Naamane, Jacques van Helden, Decio L. Eiziri...
BMCBI
2007
156views more  BMCBI 2007»
13 years 7 months ago
Large-scale clustering of CAGE tag expression data
Background: Recent analyses have suggested that many genes possess multiple transcription start sites (TSSs) that are differentially utilized in different tissues and cell lines. ...
Kazuro Shimokawa, Yuko Okamura-Oho, Takio Kurita, ...
BMCBI
2010
108views more  BMCBI 2010»
13 years 7 months ago
A genetic ensemble approach for gene-gene interaction identification
Background: It has now become clear that gene-gene interactions and gene-environment interactions are ubiquitous and fundamental mechanisms for the development of complex diseases...
Pengyi Yang, Joshua W. K. Ho, Albert Y. Zomaya, Bi...
BMCBI
2010
224views more  BMCBI 2010»
13 years 7 months ago
An adaptive optimal ensemble classifier via bagging and rank aggregation with applications to high dimensional data
Background: Generally speaking, different classifiers tend to work well for certain types of data and conversely, it is usually not known a priori which algorithm will be optimal ...
Susmita Datta, Vasyl Pihur, Somnath Datta
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