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RECOMB
2009
Springer
14 years 9 months ago
Learning Models for Aligning Protein Sequences with Predicted Secondary Structure
Accurately aligning distant protein sequences is notoriously difficult. A recent approach to improving alignment accuracy is to use additional information such as predicted seconda...
Eagu Kim, Travis J. Wheeler, John D. Kececioglu
BMCBI
2008
87views more  BMCBI 2008»
13 years 9 months ago
Protein structure search and local structure characterization
Background: Structural similarities among proteins can provide valuable insight into their functional mechanisms and relationships. As the number of available three-dimensional (3...
Shih-Yen Ku, Yuh-Jyh Hu
BMCBI
2008
130views more  BMCBI 2008»
13 years 9 months ago
IDEA: Interactive Display for Evolutionary Analyses
Background: The availability of complete genomic sequences for hundreds of organisms promises to make obtaining genome-wide estimates of substitution rates, selective constraints ...
Amy Egan, Anup Mahurkar, Jonathan Crabtree, Jonath...
BMCBI
2008
114views more  BMCBI 2008»
13 years 9 months ago
WSPMaker: a web tool for calculating selection pressure in proteins and domains using window-sliding
Background: In the study of adaptive evolution, it is important to detect the protein coding sites where natural selection is acting. In general, the ratio of the rate of non-syno...
Yong Seok Lee, Tae-Hyung Kim, Tae-Wook Kang, Won-H...
CIKM
2009
Springer
14 years 3 months ago
An analysis framework for search sequences
In this paper we present a general framework to study sequences of search activities performed by a user. Our framework provides (i) a vocabulary to discuss types of features, mod...
Qiaozhu Mei, Kristina Klinkner, Ravi Kumar, Andrew...