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» Framework for a Protein Ontology
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BIBM
2009
IEEE
155views Bioinformatics» more  BIBM 2009»
14 years 3 months ago
Towards Reliable Isoform Quantification Using RNA-Seq Data
Background: In eukaryotes, alternative splicing often generates multiple splice variants from a single gene. Here weexplore the use of RNA sequencing (RNA-Seq) datasets to address...
Brian E. Howard, Steffen Heber
ECCB
2008
IEEE
14 years 3 months ago
Functional coherence in domain interaction networks
Motivation: Extracting functional information from protein–protein interactions (PPI) poses significant challenges arising from the noisy, incomplete, generic and static nature...
Jayesh Pandey, Mehmet Koyutürk, Shankar Subra...
CMSB
2006
Springer
14 years 18 days ago
Type Inference in Systems Biology
Type checking and type inference are important concepts and methods of programming languages and software engineering. Type checking is a way to ensure some level of consistency, d...
François Fages, Sylvain Soliman
BMCBI
2010
133views more  BMCBI 2010»
13 years 9 months ago
New components of the Dictyostelium PKA pathway revealed by Bayesian analysis of expression data
Background: Identifying candidate genes in genetic networks is important for understanding regulation and biological function. Large gene expression datasets contain relevant info...
Anup Parikh, Eryong Huang, Christopher Dinh, Blaz ...
BMCBI
2005
147views more  BMCBI 2005»
13 years 8 months ago
GATA: a graphic alignment tool for comparative sequence analysis
Background: Several problems exist with current methods used to align DNA sequences for comparative sequence analysis. Most dynamic programming algorithms assume that conserved se...
David A. Nix, Michael B. Eisen