Background: A central question in cancer biology is what changes cause a healthy cell to form a tumor. Gene expression data could provide insight into this question, but it is dif...
Background: With the popularisation of high-throughput techniques, the need for procedures that help in the biological interpretation of results has increased enormously. Recently...
Background: Various high throughput methods are available for detecting regulations at the level of transcription, translation or posttranslation (e.g. phosphorylation). Integrati...
Martin Klammer, Klaus Godl, Andreas Tebbe, Christo...
for ideas, and then abstract away from these ideas to produce algorithmic processes that can create problem solutions in a bottom-up manner. We have previously described a top-dow...
Motivation: There has been considerable interest in developing computational techniques for inferring genetic regulatory networks from whole-genome expression profiles. When expre...