Sciweavers

1659 search results - page 300 / 332
» From Functional Analysis to Iterative Methods
Sort
View
BMCBI
2008
100views more  BMCBI 2008»
13 years 10 months ago
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen p
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
Guanglan Zhang, Asif M. Khan, Kellathur N. Sriniva...
BMCBI
2005
152views more  BMCBI 2005»
13 years 10 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
JMLR
2012
12 years 16 days ago
Random Search for Hyper-Parameter Optimization
Grid search and manual search are the most widely used strategies for hyper-parameter optimization. This paper shows empirically and theoretically that randomly chosen trials are ...
James Bergstra, Yoshua Bengio
DATE
2009
IEEE
116views Hardware» more  DATE 2009»
14 years 4 months ago
An MDE methodology for the development of high-integrity real-time systems
—This paper reports on experience gained and lessons learned from an intensive investigation of model-driven engineering methodology and technology for application to high-integr...
Silvia Mazzini, Stefano Puri, Tullio Vardanega
IJAR
2008
161views more  IJAR 2008»
13 years 10 months ago
Bayesian learning for a class of priors with prescribed marginals
We present Bayesian updating of an imprecise probability measure, represented by a class of precise multidimensional probability measures. Choice and analysis of our class are mot...
Hermann Held, Thomas Augustin, Elmar Kriegler