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BMCBI
2010
146views more  BMCBI 2010»
13 years 11 months ago
On the Choice and Number of Microarrays for Transcriptional Regulatory Network Inference
Background: Transcriptional regulatory network inference (TRNI) from large compendia of DNA microarrays has become a fundamental approach for discovering transcription factor (TF)...
Elissa J. Cosgrove, Timothy S. Gardner, Eric D. Ko...
BMCBI
2010
135views more  BMCBI 2010»
13 years 11 months ago
A classification approach for genotyping viral sequences based on multidimensional scaling and linear discriminant analysis
Background: Accurate classification into genotypes is critical in understanding evolution of divergent viruses. Here we report a new approach, MuLDAS, which classifies a query seq...
Ji Woong Kim, Yongju Ahn, Kichan Lee, Sung-Hee Par...
BMCBI
2010
122views more  BMCBI 2010»
13 years 11 months ago
Genome3D: A viewer-model framework for integrating and visualizing multi-scale epigenomic information within a three-dimensional
Background: New technologies are enabling the measurement of many types of genomic and epigenomic information at scales ranging from the atomic to nuclear. Much of this new data i...
Thomas M. Asbury, Matt Mitman, Jijun Tang, W. Jim ...
BMCBI
2010
164views more  BMCBI 2010»
13 years 11 months ago
Investigating the validity of current network analysis on static conglomerate networks by protein network stratification
Background: A molecular network perspective forms the foundation of systems biology. A common practice in analyzing protein-protein interaction (PPI) networks is to perform networ...
Minlu Zhang, Long J. Lu
BMCBI
2007
112views more  BMCBI 2007»
13 years 11 months ago
PFAAT version 2.0: A tool for editing, annotating, and analyzing multiple sequence alignments
Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to ...
Daniel R. Caffrey, Paul H. Dana, Vidhya Mathur, Ma...