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BIBE
2006
IEEE
135views Bioinformatics» more  BIBE 2006»
14 years 3 months ago
Evidence of Multiple Maximum Likelihood Points for a Phylogenetic Tree
An interesting and important, but largely ignored question associated with the ML method is whether there exists only a single maximum likelihood point for a given phylogenetic tr...
Bing Bing Zhou, Monther Tarawneh, Pinghao Wang, Da...
BIBE
2006
IEEE
119views Bioinformatics» more  BIBE 2006»
14 years 3 months ago
Large Grain Size Stochastic Optimization Alignment
DNA sequence alignment is a critical step in identifying homology between organisms. The most widely used alignment program, ClustalW, is known to suffer from the local minima pro...
Perry Ridge, Hyrum Carroll, Dan Sneddon, Mark J. C...
BIBE
2006
IEEE
154views Bioinformatics» more  BIBE 2006»
14 years 3 months ago
Determining Molecular Similarity for Drug Discovery using the Wavelet Riemannian Metric
Discerning the similarity between two molecules is a challenging problem in drug discovery as well as in molecular biology. The importance of this problem is due to the fact that ...
Elinor Velasquez, Emmanuel R. Yera, Rahul Singh
CEC
2005
IEEE
14 years 3 months ago
Multiobjective clustering around medoids
Abstract- The large majority of existing clustering algorithms are centered around the notion of a feature, that is, individual data items are represented by their intrinsic proper...
Julia Handl, Joshua D. Knowles
CSB
2005
IEEE
135views Bioinformatics» more  CSB 2005»
14 years 3 months ago
Relating transcription factors, modules of genes and cultivation conditions in Saccharomyces cerevisiae
Usually, the functionality of a module of co-expressed genes is derived from enrichment within the module of a particular gene annotation category. The systematic setup of the che...
Theo A. Knijnenburg, Marcel J. T. Reinders, J. M. ...