In this paper we present a novel expectation-maximization algorithm for inference of alternative splicing isoform frequencies from high-throughput transcriptome sequencing (RNA-Seq...
Marius Nicolae, Serghei Mangul, Ion I. Mandoiu, Al...
In microarray gene expression data, clusters may hide in subspaces. Traditional clustering algorithms that make use of similarity measurements in the full input space may fail to ...
Kevin Y. Yip, David W. Cheung, Michael K. Ng, Kei-...
Current motif discovery methods can only detect individual motifs in groups of protein sequences--they do not discover potentially-interacting motif pairs underlying the interacti...
GENMINER is a smart adaptation of closed itemsets based association rules extraction to genomic data. It takes advantage of the novel NORDI discretization method and of the CLOSE ...
Prediction of gene functions is a major challenge to biologists in the post-genomic era. Interactions between genes and their products compose networks and can be used to infer ge...