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WABI
2010
Springer
177views Bioinformatics» more  WABI 2010»
13 years 6 months ago
Estimation of Alternative Splicing isoform Frequencies from RNA-Seq Data
In this paper we present a novel expectation-maximization algorithm for inference of alternative splicing isoform frequencies from high-throughput transcriptome sequencing (RNA-Seq...
Marius Nicolae, Serghei Mangul, Ion I. Mandoiu, Al...
BIBE
2004
IEEE
120views Bioinformatics» more  BIBE 2004»
13 years 11 months ago
Identifying Projected Clusters from Gene Expression Profiles
In microarray gene expression data, clusters may hide in subspaces. Traditional clustering algorithms that make use of similarity measurements in the full input space may fail to ...
Kevin Y. Yip, David W. Cheung, Michael K. Ng, Kei-...
BIBE
2004
IEEE
115views Bioinformatics» more  BIBE 2004»
13 years 11 months ago
Discovering Novel Interacting Motif Pairs from Large Protein-Protein Interaction Datasets
Current motif discovery methods can only detect individual motifs in groups of protein sequences--they do not discover potentially-interacting motif pairs underlying the interacti...
Soon-Heng Tan, Wing-Kin Sung, See-Kiong Ng
BIBM
2007
IEEE
171views Bioinformatics» more  BIBM 2007»
14 years 2 months ago
GenMiner: Mining Informative Association Rules from Genomic Data
GENMINER is a smart adaptation of closed itemsets based association rules extraction to genomic data. It takes advantage of the novel NORDI discretization method and of the CLOSE ...
Ricardo Martínez, Claude Pasquier, Nicolas ...
BIBM
2007
IEEE
135views Bioinformatics» more  BIBM 2007»
14 years 2 months ago
Graph Kernel-Based Learning for Gene Function Prediction from Gene Interaction Network
Prediction of gene functions is a major challenge to biologists in the post-genomic era. Interactions between genes and their products compose networks and can be used to infer ge...
Xin Li, Zhu Zhang, Hsinchun Chen, Jiexun Li