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» From Requirements to Design: Formalizing the Key Steps
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ECCB
2002
IEEE
14 years 20 days ago
Stochastic roadmap simulation for the study of ligand-protein interactions
The dynamics of ligand-protein interactions are necessary to understand for the design of novel therapeutic agents. In this paper, we establish the use of Stochastic Roadmap Simul...
Mehmet Serkan Apaydin, Carlos Guestrin, Chris Varm...
BMCBI
2008
109views more  BMCBI 2008»
13 years 7 months ago
ConStruct: Improved construction of RNA consensus structures
Background: Aligning homologous non-coding RNAs (ncRNAs) correctly in terms of sequence and structure is an unresolved problem, due to both mathematical complexity and imperfect s...
Andreas Wilm, Kornelia Linnenbrink, Gerhard Steger
BMCBI
2005
135views more  BMCBI 2005»
13 years 7 months ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...
BMCBI
2011
12 years 11 months ago
Protein alignment algorithms with an efficient backtracking routine on multiple GPUs
Background: Pairwise sequence alignment methods are widely used in biological research. The increasing number of sequences is perceived as one of the upcoming challenges for seque...
Jacek Blazewicz, Wojciech Frohmberg, Michal Kierzy...
ICSE
2007
IEEE-ACM
14 years 1 months ago
ACL2s: "The ACL2 Sedan"
ACL2 is the latest inception of the Boyer-Moore theorem prover, the 2005 recipient of the ACM Software System Award. In the hands of an expert, it feels like a finely tuned race ...
Peter C. Dillinger, Panagiotis Manolios, Daron Vro...